Prepare the pasta per package instructions, then strain.
While the pasta is cooking, prepare the vodka sauce: Melt the butter in a large saute pan over medium heat.
Add the onion and cook for about 5 minutes, until fragrant and tender but not brown.
Add the garlic and cook for about 2 more minutes.
Turn the heat down a bit and very carefully pour the vodka slowly into the center of the pan and stir slowly and carefully to incorporate (make sure not to splash any of the vodka onto the stove or sides of the pan, it's flammable!)
Cook for about 1 minute, stirring slowly and constantly, until most of vodka is evaporated.
Add salt and pepper to taste, and hot pepper flakes and stir to coat the onions and garlic.
Add the crushed tomatoes, stir and cook for about 2 minutes
Carefully transfer the sauce to a high-speed blender or food processor (or use an immersion blender) and blend until smooth.
Pour the sauce back into the saute pan and add the coconut cream, stirring until it's incorporated into the sauce.
Taste the sauce and season with more salt and pepper if desired.
Add cooked gluten-free penne to the pan with the sauce and stir until the penne is entirely coated with the sauce.
Serve hot - delicious!